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Identifying molecular targets for the treatment of liver fibrosis and liver cancer

Project Description

Dr. Liya Pi has focused on the liver and examined reparative processes after local and environmental stresses/injuries. Her research utilizes genetically modified animal models and asks how and why aberrant expression of growth, angiogenic, and fibrotic factors in hepatic microenvironments affects: (1) hepatic progenitor cell activation and ductular reaction, (2) hepatocyte regeneration, (3) extracellular matrix remodeling and liver fibrosis, (4) liver cancer development.

Project Outcome

research presentation and manuscript publication

Project Details

Time, eligibility, and other details

Expected workloadWok duties: Gene or protein analyses by RT-PCR or immuno-blotting techniques, and PCR based mouse genotyping Expected workload:
Skills required• Ability to communicate effectively, both written and verbally • Ability to use a PC or Mac computer and Microsoft Office software (Word, Excel, PowerPoint) Excellent organizational and time management skills
Who is eligibleStudents majoring in biology or public health
Core partners
Sponsoring partyYes, this is a NIH-sponsored project.
Volunteer, Paid, or Credit-eligible?volunteer

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