Project Description Tissue resident macrophage function has emerged as a critical component controlling the balance between organ health and disease, and disruption of tissue homeostasis can lead to disease. Cancer cells adopt mechanisms to escape immune surveillance, evade growth signals, and others, by participating in complex interactions with healthy immune cells to orchestrate breast cancer […]

Project Description Stem cells play pivotal roles in maintaining tissue and organ homeostasis in adults, particularly for effective tissue repair post-injury. In the intestine, the expansion of the intestinal stem cell (ISC) pool involves both the symmetric division of resident ISCs and the regeneration of ISCs from terminally committed cells through dedifferentiation. We aim to […]

Hua Lu, MB (US MS equivalent), PhD (School of Medicine) Project Description The Lu laboratory is interested in understanding the molecular and biochemical basis that underlies physiological and pathological signalingpathways (growth, metabolic, hypoxia, or DNA damage signals), which lead to gene expression and subsequent cell growth arrest, differentiation,senescence, autophagy, or apoptosis. Project Details Time, eligibility, […]

Arthur Lustig, PhD of Tulane University School of Medicine Project Description My laboratory studies the basic processes that influence the stability of repeated sequences, using the fungus Aspergllus flavus as a model system.We have been investigating the unique properties present at he ends of chromosomes, called telomeres, on recombinational stability andheterochromatin formation using both bioinformatic […]