Project Description A specific and rapid cell ablation model mediated has been developed by my lab for nearly years. This ablation model was created by my lab via utilization of unique feature of bacterial toxin, intemedilysis (ILY)(Nat Med. 2008 Jan;14(1):98-103). ILY only lyzes human CD59 but not cells from any other species via exclusive interaction […]

Lab Description Studies the therapeutic potential of gene therapy in the treatment of AIDS, lysosomal storage diseases, and the use of hematopoietic stem cells. Topics include tissue-specific expression of therapeutic genes and immunomodulatory effects of gene expression. This intersection has clinical relevance for multiple diseases and therapeutic modalities including gene therapy strategies, transplantation, immunotherapy and […]