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Remote Collection of Dental Pulp Stem Cells to Study Human Neurogenetic Disorders.

Lawrence Reiter, School of Medicine

Project Description

In the Reiter laboratory we utilize a unique resource to study rare neurogenetic syndromes involving autism, epilepsy, sleep disorder and other aspects of human disease. We do this by extracting stem cells from deciduous teeth (baby teeth) from children with these rare syndromes. This process involves evaluating a genetics report to determine eligibility for the study and remote autism assessment using the Social Communication Questionnaire. We currently have open collections for multiple human disorders including Prader-Willi, Angelman, Duplication 15q and other rare syndromes. We send subjects and caregivers a collection kit containing a tube of media and a return package so that when a child’s tooth falls out they can quickly send it to our lab for extraction of the DPSC or dental pulp stem cells. We currently house a collection of >200 DPSC lines from 14 different syndromes and have published >15 manuscripts on these lines.
We are looking for an eager medical student who can review our current DPSC records, update inconsistencies in the Excel sheets, learn to read the genetics reports, interface with caregivers online, record SCQ scores, send out kits for collections and eventually to extract DPSC and freeze back cell lines for more advanced studies. There is also potential for this student to learn to write and update human subjects research protection documents (IRBs).

Project Details

Faculty Supervisor Lawrence Reiter
Project Start Date 10/01/2025
Number of Spots Available 1
Project Type Translational
Location On-Site
Type of Research Lab-based, Clinical Trial, Other
Project Duration Long-term (3+ years)
Supervisor Faculty
Project Expertise https://medicine.tulane.edu/departments/physiology/faculty/lawrence-t-reiter-phd

Prerequisites or Preferred Skills

Good organizational skills. Familiarity with Excel spreadsheets and computing skills (Database management a plus).

Expected Time Commitment

10-15hrs/week depending on requests from subjects and workload.

Required Forms

Cover Letter and CV.

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