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Using Precision Cut Lung Slices to Model Pneumonia

Jay Kolls, Medicine - CTRII - Center For Translational Research in Infection and Inflammation

    Project Description

    This project uses a novel form of tissue culture to study the early events in pneumonia such as pathogen adherence and growth in the lung. This system can be used to study the role of lung and blood macrophages in pathogen killing as well as be used to test novel antibiotics and immune-based therapies.

    Project Outcome

    The student will learn tissue culture, microscopy, and gene expression by using real-time PCR or RNA sequencing.

    Project Details

    Time, eligibility, and other details

    Expected workload10-20 hours per week during the semester or 40 hours per week over the summer.
    Skills requiredPrior lab experince is prefeerred but not required
    Who is eligibleSophomores to Seniors are eligible
    Core partnersNIH
    Sponsoring partyThis project is funded by NIH.
    Volunteer, Paid, or Credit-eligible?paid or credit eligible

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