Project Description The long-term goal of my research program is to uncover the epigenetic mechanisms, especially histone acetylation and deacetylation, responsible for kidney formation and abnormality. Our studies will provide new insights into the epigenetics of kidney development and open new avenues to novel strategies for the prevention and treatment of kidney diseases and associated […]

Project Description Diabetes induces vascular complications that greatly increase morbidity and mortality but are not attenuated by proper control of blood glucose. We previously demonstrated that diabetes increases two co-transcribed microRNAs, miR-221-3p and miR-222-3p (miR-221/222), in vascular smooth muscle cells (VSMCs) to promote intimal thickening. Diabetic VSMC-derived exosomes (DVEs) contain elevated levels of these miRNAs […]

Project Description Using large state-of-the-art databases, we are studying relationships of abnormal DNA hypermethylation and hypomethylation in cancer to transcription. This research is uncovering insights into the functionality of these aberrations by comparing normal developmental changes in DNA methylation, chromatin epigenetics, and gene expression to those in cancer. Our findings are relevant to the discovery […]

Project Description Stem cells play pivotal roles in maintaining tissue and organ homeostasis in adults, particularly for effective tissue repair post-injury. In the intestine, the expansion of the intestinal stem cell (ISC) pool involves both the symmetric division of resident ISCs and the regeneration of ISCs from terminally committed cells through dedifferentiation. We aim to […]

Michael Hoerger, PhD, MSCR, MBA (Psychology) Project Description Our lab conducts health psychology research aimed at 1) reducing the burden of cancer 2) reducing the burden of the COVID-19 pandemic Project Details Time, eligibility, and other details Expected workload varies (contact project organizer) Contact Info mhoerger@tulane.edu Who is eligible Students Additional Info Ideal lab for […]

Chad Steele (Microbiology and Immunology) Project Description We are primary lung immunology lab investigated immune responses to acute fungal exposure (fungal pneumonia) and chronic fungal exposure(allergic fungal asthma). We also have a project investigating neuroimmune responses during CNS fungal infection Project Details Time, eligibility, and other details Expected workload varies (contact project organizer) Contact Info […]

Project Description This project uses a novel form of tissue culture to study the early events in pneumonia such as pathogen adherence and growth in the lung. This system can be used to study the role of lung and blood macrophages in pathogen killing as well as be used to test novel antibiotics and immune-based […]

T. Cooper Woods, PhD (Department of Physiology and Medicine) Project Description We are focused in a variety of ways in investigating the roles of non-coding RNAs in atherosclerosis. We have a focus on the the effects of diabeteson atherosclerosis. Project Details Time, eligibility, and other details Who is eligible? Some experience with PCR preferred Volunteer, […]

Project Description Aging and Prostate Cancer: Dr. Zhang has a long-standing interest in prostate cancer, particularly in aging’s contribution to prostate carcinogenesis and the efficacies of candidate aging-associated prostate cancer interventions. We are currently working on (1) identifying associations between Th17/Treg ratio alteration and human PCa progression associated with advanced aging; (2) defining how aging-associated […]

Asim B. Abdel-Mageed, DVM, PhD, School of Medicine Project Description While his long-standing translational research interests focus on molecular determinants of prostate cancer progression and prostate cancer health disparities, his current research also focuses on understanding the role of tumor-derived exosomes in mediating prostate cancer progression, with special emphasis on racial disparity of prostate cancer. Importantly, his research […]