Project Description Mitochondria associate with the plasma membrane, and this has been observed in electron micrographs since the 1950s. This behavior is particularly evident in nerve terminals. However, the significance of this behavior is unknown. Working closely with a Research Scientist, you will be asked to culture motor neurons and use a sophisticated fluorescence microscopy […]

Project Description Diabetes induces vascular complications that greatly increase morbidity and mortality but are not attenuated by proper control of blood glucose. We previously demonstrated that diabetes increases two co-transcribed microRNAs, miR-221-3p and miR-222-3p (miR-221/222), in vascular smooth muscle cells (VSMCs) to promote intimal thickening. Diabetic VSMC-derived exosomes (DVEs) contain elevated levels of these miRNAs […]

T. Cooper Woods, PhD (Department of Physiology and Medicine) Project Description We are focused in a variety of ways in investigating the roles of non-coding RNAs in atherosclerosis. We have a focus on the the effects of diabeteson atherosclerosis. Project Details Time, eligibility, and other details Who is eligible? Some experience with PCR preferred Volunteer, […]

Contact twoods3@tulane.edu

Lab Description Hypertension is one of the most prevalent conditions. The renin-angiotensin system (RAS) is known to play important roles in blood pressure control. Since intrarenal RAS is activated in many forms of hypertension, the renal RAS is acknowledged as a key target for clinical and biochemical studies. Recent studies have revealed that RAS and […]

Lab Description Research in my lab is focused on the intrarenal regulation of the RAS in hypertension. My training in molecular genetics and renal physiology with emphasis on experimental hypertension has allowed focusing my efforts on investigating the functional role and the regulation of intrarenal RAS genes in the pathophysiology of hypertension and related renal […]

Project Description The primary goal of our research is to determine the genetic and molecular basis of hypertension and cardiovascular disorders in age- and sex-dependent manner.  The long-term objectives of our research projects are to determine the molecular and cellular action of atrial and brain natriuretic peptides (ANP, BNP) that control blood pressure and cardiovascular […]

Lab Description Research programs in Dr. Navar’s laboratory investigate hormonal and paracrine mechanisms regulating renal hemodynamics, glomerular filtration rate (GFR), and sodium excretion. Intense activity is also focused on the pathophysiology of hypertension and the role of the intrarenal renin angiotensin system (RAS) in altering kidney function to lead to in angiotensin II dependent hypertension […]

Lab Description Central Neural Control of the Autonomic Nervous System: Using whole-cell patch-clamp electrophysiological techniques combined with calcium imaging, neuro-pharmacological, immunochemical, and molecular biological methods, we are conducting studies to determine the synaptic organization, modulation, and plasticity of neuronal networks involved in central neural control of the autonomic nervous system, including cardiovascular function. Goals of […]