List a Project
LCRC Allocation; FOXOS Role in Cancer
Suzana Savkovic, PhD, School of Medicine Lab Description The main focus of my lab has been to study the role of the transcription factor FOXO3 in inflammation-mediated tumor growth, with a specific focus on the colonic epithelium and colon cancer. First, we have demonstrated that proinflammatory stimuli, such as bacterial products and cytokines, cause a […]
Targeted Kinase Inhibition as a Novel Therapy for Incurable Childhood Cancer; LCRC Allocation
Sean Bong Lee, PhD, School of Medicine Lab Description The primary interest of our laboratory is to understand how oncogenic events such as a chromosomal translocation lead to cancer. Ewing’s sarcoma and related small round cell tumors have a distinct characteristic, which involves a chromosomal translocation of the Ewing’s sarcoma gene (EWS) to various transcription […]
Gragert Lab
Loren Gragert, PhD, School of Medicine Lab Information Projects – LCRC Allocation – HLA Bioinformatics Project Contact lgragert@tulane.edu
Virus Infections and Hepatocellular Carcinoma in a Humanized Mouse Model; Exosome-based Serum Biomarkers for Chronic Liver Disease and Cirrhosis
Srikanta Dash, PhD, School of Medicine Project Overview Hepatitis C virus (HCV) is a positive-strand RNA virus replicate exclusively in the cytoplasm. HCV infection compromises the natural defense mechanism of the liver leading to high rate of chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC). The incidence of HCC is expected to be decreased after […]
Norton Lab
Project Description My research focuses on induction of protection immunity, typically focusing on mucosal immunity, infection, and adjuvants. My lab uses bacterial ADP-ribosylating enterotoxins derived from E. coli for the manipulation of protective immunity, including the novel adjuvants dmLT and LTA1. In addition, I am interested in host factors and biomarkers of protective immunity, including […]
A broad-spectrum OMV vaccine against aerosolized B. pseudomallei and B. mallei
Project Description Contact Email lmorici@tulane.edu
Novel delivery formulations for vaccines, antimicrobials, and therapeutic drugs
Project Description The majority of pathogens enter the body through mucosal surfaces. To achieve protection at these sites of entry, my research focuses on vaccine development, particularly investigating non-parenteral (needle-free) immunization techniques. Transcutaneous immunization is one technique that offers many potential benefits over traditional vaccine delivery, including induction of a mucosal immune response. With a […]
Multi-omics and Trans-omics Biostatistics and Bioinformatics Genetics of Complex Diseases
Hongwen Deng, PhD (School of Medicine) Project Description Our research group is interested in genetic dissection of human complex diseases using the state-of-the-art multi- and inter-disciplinary approachesof genomic technologies, and statistical and bioinformatical methods. The complex disease we are focusing on is osteoporosis, which is a prevalent,debilitating disorder characterized by bone fragility and an increased […]
Cancer Mechanisms, Metabolism, Biology and Drug Discovery involving p53 and c-Myc pathways
Hua Lu, MB (US MS equivalent), PhD (School of Medicine) Project Description The Lu laboratory is interested in understanding the molecular and biochemical basis that underlies physiological and pathological signalingpathways (growth, metabolic, hypoxia, or DNA damage signals), which lead to gene expression and subsequent cell growth arrest, differentiation,senescence, autophagy, or apoptosis. Project Details Time, eligibility, […]
Pleiotropic Effects of the Prorenin Receptor (PRR) in the Collecting Duct During Intrarenal RAS Activation
Lab Description Research in my lab is focused on the intrarenal regulation of the RAS in hypertension. My training in molecular genetics and renal physiology with emphasis on experimental hypertension has allowed focusing my efforts on investigating the functional role and the regulation of intrarenal RAS genes in the pathophysiology of hypertension and related renal […]