List a Project
Role of VSMC-Derived Exosomes in the Cardiovascular Complications of Diabetes + Biomarkers during carotid plaque rupture
Contact twoods3@tulane.edu
Effect of SOCSs on Intrarenal RAS Regulation and Its Molecular Mechanisms
Lab Description Hypertension is one of the most prevalent conditions. The renin-angiotensin system (RAS) is known to play important roles in blood pressure control. Since intrarenal RAS is activated in many forms of hypertension, the renal RAS is acknowledged as a key target for clinical and biochemical studies. Recent studies have revealed that RAS and […]
Pleiotropic Effects of the Prorenin Receptor (PRR) in the Collecting Duct During Intrarenal RAS Activation
Lab Description Research in my lab is focused on the intrarenal regulation of the RAS in hypertension. My training in molecular genetics and renal physiology with emphasis on experimental hypertension has allowed focusing my efforts on investigating the functional role and the regulation of intrarenal RAS genes in the pathophysiology of hypertension and related renal […]
Study of ANP Receptor: Gene Targeting and Expression
Project Description The primary goal of our research is to determine the genetic and molecular basis of hypertension and cardiovascular disorders in age- and sex-dependent manner.  The long-term objectives of our research projects are to determine the molecular and cellular action of atrial and brain natriuretic peptides (ANP, BNP) that control blood pressure and cardiovascular […]
Navar Lab
Lab Description Research programs in Dr. Navar’s laboratory investigate hormonal and paracrine mechanisms regulating renal hemodynamics, glomerular filtration rate (GFR), and sodium excretion. Intense activity is also focused on the pathophysiology of hypertension and the role of the intrarenal renin angiotensin system (RAS) in altering kidney function to lead to in angiotensin II dependent hypertension […]
Sympathetic Control and Hypertension via Brainstem Cannabinoid Signaling
Lab Description Central Neural Control of the Autonomic Nervous System: Using whole-cell patch-clamp electrophysiological techniques combined with calcium imaging, neuro-pharmacological, immunochemical, and molecular biological methods, we are conducting studies to determine the synaptic organization, modulation, and plasticity of neuronal networks involved in central neural control of the autonomic nervous system, including cardiovascular function. Goals of […]
Estrogen Mediated Protection Against Stroke: Mitochondria as Subcellular Targets of Nitric Oxide
Contact irutkai@tulane.edu
Cortical Synaptic Dynamics During Learning in the Aging Brain
Lab Description Cortical circuits show a certain degree of plasticity during normal brain functions (e.g., sensory stimulation, memory storage and learning). This plasticity can be altered during development, e.g., autism, but also when the brain is perturbed/damaged (for example during sensory deprivation or stroke). Using state-of-the-art imaging techniques, i.e. two-photon laser microscopy in combination with […]
Katakam Lab
Prasad Katakam, MD, PhD, School of Medicine Projects Contact Not accepting students through Spring 2025 pkatakam@tulane.edu
 The Intersection of Gene Therapy, Hematopoietic Stem Cells and the Response of the Immune System.
Lab Description Studies the therapeutic potential of gene therapy in the treatment of AIDS, lysosomal storage diseases, and the use of hematopoietic stem cells. Topics include tissue-specific expression of therapeutic genes and immunomodulatory effects of gene expression. This intersection has clinical relevance for multiple diseases and therapeutic modalities including gene therapy strategies, transplantation, immunotherapy and […]
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