List a Project
Pediatrics Research Inquiries
Project Description The Department of Pediatrics (Tulane University School of Medicine) has numerous opportunities open for undergraduates. Some faculty have lab listings on TRN for specific projects – other students may be looking for opportunities beyond what is listed. Students interested in participating in pediatrics research should apply, including their general areas of interest (i.e. […]
Undergraduate Research Assistant
Project Description I am seeking to hire up to 2 undergraduate research assistants (RAs) for the 2024-2025 academic year as part of a pilot program. The RA will work closely with me as a partner in research to help advance three ongoing projects as part of my research agenda on equity in taxation, especially gender […]
Fluorescence Microscopy Analysis of an Unexplained Mitochondrial Behavior
Project Description Mitochondria associate with the plasma membrane, and this has been observed in electron micrographs since the 1950s. This behavior is particularly evident in nerve terminals. However, the significance of this behavior is unknown. Working closely with a Research Scientist, you will be asked to culture motor neurons and use a sophisticated fluorescence microscopy […]
Zhou Laboratory – Lung Repair and Regeneration
Project Description Our lab focuses on the mechanobiology of lung injury, repair, and regeneration, investigating how biomechanical signals from the extracellular matrix (ECM) influence the progression and resolution of lung fibrosis. We have previously identified key roles of altered matrix mechanics in modulating gene expression and promoting the pro-fibrotic traits of lung fibroblasts and alveolar […]
Epigenetic regulation of kidney development and disease
Project Description The long-term goal of my research program is to uncover the epigenetic mechanisms, especially histone acetylation and deacetylation, responsible for kidney formation and abnormality. Our studies will provide new insights into the epigenetics of kidney development and open new avenues to novel strategies for the prevention and treatment of kidney diseases and associated […]
Exosome transfer of non-coding RNA in the Cardiovascular Complications of Diabetes
Project Description Diabetes induces vascular complications that greatly increase morbidity and mortality but are not attenuated by proper control of blood glucose. We previously demonstrated that diabetes increases two co-transcribed microRNAs, miR-221-3p and miR-222-3p (miR-221/222), in vascular smooth muscle cells (VSMCs) to promote intimal thickening. Diabetic VSMC-derived exosomes (DVEs) contain elevated levels of these miRNAs […]
Aberrant DNA methylation associated with transcriptional abnormalities in cancer
      Project Description Using large state-of-the-art databases, we are studying relationships of abnormal DNA hypermethylation and hypomethylation in cancer to transcription. This research is uncovering insights into the functionality of these aberrations by comparing normal developmental changes in DNA methylation, chromatin epigenetics, and gene expression to those in cancer. Our findings are relevant […]
Analysis of preconception data
Project Description Establishing the pre-pregnancy nutritional factors associated with delivery of healthy infants ideally involves assessing nutrition prospectively, accurately, and in a way that generalizes to diverse populations. Several different diets, including the Mediterranean, DASH, Fit for Delivery, FIGO Nutrition, and the Fertility Diet have been recommended for women planning to conceive. However, approximately 45% […]
The Drosophila model for studying the stem cell regeneration
Project Description Stem cells play pivotal roles in maintaining tissue and organ homeostasis in adults, particularly for effective tissue repair post-injury. In the intestine, the expansion of the intestinal stem cell (ISC) pool involves both the symmetric division of resident ISCs and the regeneration of ISCs from terminally committed cells through dedifferentiation. We aim to […]
How do antibacterial agents affect lipid bilayer rigidity and mobility?
Project Description We developed an approach of putting a unique vibrational label into a lipid bilayer at a desired depth in the hydrophobic portion of the bilayer. The label is capable of measuring accurately the rigidity of the bilayer via vibrational spectroscopy (FTIR and 2DIR). The project involved testing how the bilayer interior is affected […]