List a Project
The Regulation of Kidney Development by Histone Deacetylases
Hongbing Liu, PhD, School of Medicine Projects -The roles of histone deacetyalses (HDACs) in kidney development-HDACs and kidney cancers-Developmental programming of chronic disease by HDACs Contact hliu8@tulane.edu
Epigenetic Control of Nephron Progenitor Cell Renewal and Fate; Kidney Development: Cell Fate and Precursors of Disease in the Young and Adult
Samir El-Dahr, MD, School of Medicine Lab Description Clinical Research Interests: 1.  Pediatric hypertension (high blood pressure)2.  Nephrotic syndrome (swelling due to loss of protein in the urine)3.  Hematuria (blood in the urine)4.  Chronic kidney disease (abnormal kidney function) and kidney failure5.  Dialysis6.  Kidney transplantation Contact seldahr@tulane.edu
Wu Lab
Tong Wu, MD, PhD, School of Medicine Lab Description Dr. Wu’s basic research centers on the molecular mechanisms of inflammation and carcinogenesis, with a special emphasis on the pathogenesis of liver cancer and inflammatory liver diseases. His laboratory focuses on the biological functions and molecular mechanisms of several signaling molecules/cascades including miRNAs, lncRNAs, TGF-beta, Hedgehog, […]
LCRC Allocation; FOXOS Role in Cancer
Suzana Savkovic, PhD, School of Medicine Lab Description The main focus of my lab has been to study the role of the transcription factor FOXO3 in inflammation-mediated tumor growth, with a specific focus on the colonic epithelium and colon cancer. First, we have demonstrated that proinflammatory stimuli, such as bacterial products and cytokines, cause a […]
Environmental Exposures and Lung Carcinogenesis
Gilbert Morris, PhD, School of Medicine Lab Description The Morris laboratory is interested in the molecular biology of lung injury and repair with a particular interest in fibrogenesis and carcinogenesis. a. Modeling lung tumorigenesis in mice. Our laboratory has demonstrated expression of the p53 tumor suppressor protein at sites of fibrogenesis after inhalation exposure of […]
Targeted Kinase Inhibition as a Novel Therapy for Incurable Childhood Cancer; LCRC Allocation
Sean Bong Lee, PhD, School of Medicine Lab Description The primary interest of our laboratory is to understand how oncogenic events such as a chromosomal translocation lead to cancer. Ewing’s sarcoma and related small round cell tumors have a distinct characteristic, which involves a chromosomal translocation of the Ewing’s sarcoma gene (EWS) to various transcription […]
Virus Infections and Hepatocellular Carcinoma in a Humanized Mouse Model; Exosome-based Serum Biomarkers for Chronic Liver Disease and Cirrhosis
Srikanta Dash, PhD, School of Medicine Project Overview Hepatitis C virus (HCV) is a positive-strand RNA virus replicate exclusively in the cytoplasm. HCV infection compromises the natural defense mechanism of the liver leading to high rate of chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC). The incidence of HCC is expected to be decreased after […]
Viral infections, the host immune response, and therapeutic strategies targeting viral infections and other disease states
Kislay Parvatiyar, PhD, School of Medicine Project Description Innate immune pathways are found as far back as early branching metazoans, however these pathways have evolved extensively and become increasingly complex in higher organisms. Indeed, the innate immune system is known to defend against invading pathogens via a suite of germline encoded pattern recognition receptors (PRRs) […]
Norton Lab
Project Description My research focuses on induction of protection immunity, typically focusing on mucosal immunity, infection, and adjuvants. My lab uses bacterial ADP-ribosylating enterotoxins derived from E. coli for the manipulation of protective immunity, including the novel adjuvants dmLT and LTA1. In addition, I am interested in host factors and biomarkers of protective immunity, including […]
A broad-spectrum OMV vaccine against aerosolized B. pseudomallei and B. mallei
Project Description Contact Email lmorici@tulane.edu